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Monday, December 22, 2025

A Fascinating Paradox Regarding Vitamin, Illness Threat, And Survival – BionicOldGuy


Dr. Raphael Cuomo, a professor on the College of California, San Diego College of Medication who’s work I’ve talked about beforehand, known as my consideration to an enchanting latest paper he wrote. It’s about “dietary epidemiology danger–survival paradox”, for which the time period “Cuomo’s Paradox” has additionally been coined. There may be additionally a very good abstract of the paradox in this youtube video. To summarize, there are well being and diet suggestions to cut back the chance of buying situations like heart problems and sure kinds of most cancers. However the paradox is that if you have already got one in every of these illnesses, these similar suggestions can develop into contraindicated as a result of they will now enhance the chance of dying from the illness. An vital exemple is weight problems, which is properly generally known as a danger issue. However carrying some further kilos might be protecting after you have already got a illness.

Instance of Cuomo’s Paradox: Impact of being obese, consuming alcohol, and ldl cholesterol on affected person’s with coronary heart failure (https://www.youtube.com/watch?v=qW_Q09R0ON0)

Proof for extra results like this (like the consequences of alcohol and ldl cholesterol) are lined within the paper. Dr. Cuomo is cautious to level out that we could not but have sufficient data to vary well being suggestions, however extra analysis is unquestionably wanted on this intriguing paradox. Here’s a hyperlink to the complete textual content within the Journal of Vitamin.



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